Critical Care
ICU management and systemic complications
Acute kidney injury (AKI) affects approximately 20-25% of major burn patients and carries mortality rates exceeding 50% when it develops. Early AKI is driven by hypovolemia, myoglobinuria, and direct
Anesthesia for burn surgery requires adaptation to altered pharmacokinetics, airway challenges, thermoregulation demands, and massive fluid shifts. Succinylcholine is contraindicated after the first 2
Burn-induced coagulopathy involves both consumptive and dilutional mechanisms, with disseminated intravascular coagulation (DIC) as a life-threatening complication. Burn severity, particularly the bur
Post-burn hyperglycemia driven by the hypermetabolic response is associated with increased infection, sepsis, and mortality. The critical care field moved from tight glucose control (Van den Berghe 20
Burn pain is severe, prolonged, and multidimensional, spanning background, procedural, breakthrough, and neuropathic components. Multimodal analgesia combining opioids, non-opioid adjuncts (NSAIDs, ac
Delirium occurs in up to 47% of burn ICU patients and is independently associated with older age, intensive care, and number of interventions under anesthesia. Analgosedation strategies yield the most
Burn-specific sepsis criteria (ABA 2007 consensus) are required because conventional SIRS/Sepsis-3 definitions are unreliable in the hyperinflammatory burn state. Platelet trends, vital sign pattern s
Burn patients are among the most heavily transfused surgical populations. A restrictive RBC transfusion threshold (Hb less than 7-8 g/dL) appears safe and reduces transfusion volume without increasing
Burn patients are at high risk for VTE due to immobility, central venous access, systemic inflammation, and hypercoagulability. VTE incidence in prospectively screened burn populations ranges from 6-8